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Open access Sep 2026

Multi‐site sequencing supports dual‐track evolution and identifies candidate metastasis‐associated factors in gastric cancer ovarian metastasis

Abstract Background Gastric cancer ovarian metastasis (GCOM) is an aggressive clinical entity whose evolutionary dissemination routes and molecular features remain incompletely defined. Methods We performed whole‐exome sequencing and patient‐level phylogenetic reconstruction of 81 spatially distinct tumour specimens fr...

Pei-Yu Zhu, Xiao-Fang Xing, Ke Ji et al. · 0 citations
Open access Sep 2026

A combined tumor burden–based nomogram for synchronous esophageal and gastric cancers: development and external validation

Synchronous dual-primary esophageal and gastric cancers (SEGC) are rare upper gastrointestinal malignancies presenting substantial challenges for prognostic assessment and individualized clinical evaluation. Conventional single-organ staging systems inadequately capture the cumulative tumor burden of synchronous ca...

Meng Xie, Jing Wang, Zi-Yu Jia et al. · 0 citations

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