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Ke-Long Tang

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Review Open access Aug 2026

The Pyrazolone Scaffold: A Privileged Motif for Molecular Hybridization in Drug Discovery

This review comprehensively summarizes recent advancements in the structural optimization of pyrazolone‐based compounds, highlighting how molecular hybridization drives polypharmacology against complex conditions, including neurodegenerative disorders, inflammation, metabolic syndromes, cancer, and infectious diseases.

Ke-Long Tang, Yao Liu, Jingning Luo et al. · 0 citations

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