Author

Ke-Man Xu

2 papers indexed here

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Open access Sep 2026

Integrative Omics Analysis Reveals a CD206+ Macrophage/Dendritic Cell–CD155–TIGIT+ Regulatory T Cell Axis as a Protective Immune Checkpoint Pathway in Atherosclerosis Progression

RNA sequencing (RNA-seq) analysis revealed transcriptional features indicative of sustained immunosuppression within regulatory T cells (Tregs) isolated from atherosclerotic tissues, highlighting the critical contribution of immune checkpoint (ICP) receptor–ligand interactions to atherosclerosis progression. To compreh...

Ying Shao, Fatma Saaoud, Mohammed Ben Issa et al. · Barrier immunity · 0 citations

Review Sep 2026

The regulatory and therapeutic potential of transposable elements in cancer and inflammatory diseases.

Transposable elements (TEs), commonly known as "jumping genes," constitute nearly half of the human genome and are increasingly recognized as important regulators of gene expression, chromatin organization, and immune signaling. Although most TEs are epigenetically silenced under physiological conditions, aging, chroni...

Ke-Man Xu, Juan-Juan Liu, Fatma Saaoud et al. · Pharmacology and Therapeutic... · 0 citations