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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Ke Wang

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Clinical trial Open access Aug 2026

Randomized phase 2 trial of a PARP inhibitor TSL-1502 in germline BRCA-mutated, HER2-negative locally advanced/metastatic breast cancer

Glucuronide prodrug strategies may enhance target specificity and reduce the toxicity of PARP inhibitors, but no clinical evaluation has been performed. We evaluated TSL-1502, a novel glucuronide prodrug of a PARP inhibitor, in a randomized, open-label, phase 2 study at 28 sites in China (NCT05420779). Eligible patient...

B. Lan, Faliang Xu, Tao Sun et al. · 0 citations
Open access Aug 2026

Interpretable machine learning prognostication of gastroenteropancreatic neuroendocrine tumors across Chinese and United States cohorts

Background Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) display marked clinical heterogeneity, and conventional prognostic indicators such as TNM stage and Ki-67 index provide limited individualized risk discrimination. We aimed to develop and externally validate interpretable machine learning models for sur...

Yang-Wei Fan, Yu-Qian Yang, Ke Wang et al. · 0 citations

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