Open access
Jan 2026
The AGEs/RAGE Axis Contributes to Myocardial Cell Death in Type 1 Diabetic Cardiomyopathy via the ROS/NF‐κB/NLRP3 Inflammasome Pathway
Background Type 1 diabetes mellitus (T1DM) cardiomyopathy is a severe complication that typically follows an insidious onset and then progresses rapidly to heart failure and premature death. AGEs accumulate in the myocardium under hyperglycemic conditions and have emerged as important mediators of this diabetic complic...
Xiao-Qun Li, Shu-Jie Chen, Ke Wang et al.
· Journal of Diabetes Research · 0 citations