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#artificial intelligence Open access Sep 2026

Dis-GPT and DIS Chatflow Reports for Nifedipine Controlled-Release Tablet Release-Phenotype Assessment

This dataset supports the manuscript “Time-Lapse Macro Imaging and LLM-Assisted Similarity Assessment of Release Behavior in Nifedipine Controlled-Release Tablets.” Sixteen marketed nifedipine controlled-release tablet products, including the reference Adalat OROS (sample 01) and 15 generic products (samples 02–16), were imaged in triplicate for 36 h at 37 ± 0.5 °C under sequential media conditions (pH 1.0 for 2 h followed by pH 6.8 for 34 h). The deposit contains qualitative image-based comparison reports generated using two separate artificial-intelligence-assisted methods: 16 reports produced using Dis-GPT and 48 reports produced using DIS Chatflow, comprising three independent analyses for each sample. Sample 01 was used as the reference. The terms “similar” and “different” refer to image-based release phenotypes and do not establish chemical identity, batch equivalence, pharmaceutical equivalence, clinical efficacy, or product quality equivalence. Original source images and videos are not included in this deposit.

Ke Xu · 0 citations

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