Hepatitis B virus (HBV) infection remains a significant global health challenge and is a leading cause of chronic liver diseases, including cirrhosis and hepatocellular carcinoma. Although nucleos(t)ide analogs and interferon-based therapies suppress viral replication, they do not eliminate the viral reservoir, highlig...
Yumi Itoh, Chiharu Morita, Jin-Zi Cui et al.· Antiviral Research· 0 citations
Profiling of newly synthesized proteins (NSPs) provides access to dynamic changes in protein production that accompany acute cellular responses. Bioorthogonal noncanonical amino acid tagging (BONCAT)-based approaches enable selective labeling of NSPs; however, their broader application remains constrained by labor-inte...
Y. Kimura, Tomoko Akiyama, Tatsuhiro Kobashi et al.· Journal of Proteome Research· 0 citations
BA.3.3.2.2 preserves class 1/2 antibody epitopes, providing a mechanistic basis for cross-neutralization and suggesting a potential therapeutic window for sipavibart should BA.3.3.2.2 expand globally, pending clinical confirmation.
Kei Miyakawa, Kaori Sano, Yohei Seki et al.· International Journal of Inf...· 0 citations
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