Author

Keisuke Yoshida

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Open access Aug 2026

EV-Tracer enables lineage-resolved detection and molecular profiling of extracellular vesicle-associated signals in cancer–fibroblast co-culture

EV-Tracer, a CD63-based dual-fluorescence tracing and capture system for detecting, isolating, and profiling lineage-associated EV fractions, was developed and provides a useful platform for dissecting lineage-associated EV communication.

Yutaka Naito, Chiaki Hori, Keisuke Yoshida et al. · bioRxiv · 0 citations

Open access Sep 2026

A patient-derived LMX1B variant causes tissue-specific manifestations of nail-patella syndrome in mice

The findings show that the effects of an LMX1B variant cannot be predicted from its residual activity alone, and the susceptibility of each organ may depend on the cellular and genetic context in which the variant acts.

T. Amano, Keisuke Yoshida, F. Sultana et al. · bioRxiv · 0 citations

Open access Aug 2026

Aberrant expression of the PREX2-MAGI2 axis modulates myofibroblast differentiation in pulmonary fibrosis.

It is suggested that MAGI2 acts as a negative regulator of myofibroblast differentiation by stabilizing PTEN, whereas PREX2 is aberrantly expressed in the fibrotic milieu, negatively modulating MAGI2, thereby accelerating pulmonary fibrosis.

Yozo Sato, K. Kamio, Yasuhiro Terasaki et al. · American Journal of Physiolo... · 0 citations