Mid-life candidate vascular plasma biomarkers are associated with MRI markers of vascular brain injury and amyloid- and tau-PET in cognitively healthy adults.
BackgroundIdentifying candidate biomarkers for preclinical dementia could improve our understanding of underlying biological pathways leading to vascular brain injury (VBI) and neurodegeneration.ObjectiveTo identify plasma protein markers of MRI markers of VBI and amyloid- and tau-PET burden in cognitively healthy adul...