Kelong Chen

The molecular mechanisms of Guizhi Fuling Pills in ameliorating Alzheimer’s disease-like cognitive impairment: insights from transcriptomics, metabolomics, and gut microbiome

GFP improved learning and memory function in aged mice, ameliorated hippocampal neuronal morphology, and reduced p-Tau protein deposition through multiple mechanisms, including repair of the BBB, attenuation of inflammatory responses, and modulation of the gut microbiota and metabolic disorders.