Author

Kenichi G. N. Suzuki

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Open access Aug 2026

Cis glycan–glycan interactions organize membrane nanodomains that tune receptor signaling

The plasma membrane (PM) is generally viewed as organized by coordinated interactions among proteins and lipids, largely overlooking the cell’s most extensive surface chemistry, the glycan layer. Here, we directly detect specific cis glycan–glycan interactions using single-molecule imaging of 39 chemically synthesized...

Kenichi G. N. Suzuki, N. Komura, Sachi Asano et al. · Nature Communications · 0 citations

Sep 2026

Cooperative Membrane Recognition by Lipid-Sensing and Kinase Domains Shapes Membrane-Bound States of AKT

The PI3K/AKT signaling pathway is triggered by the recruitment of AKT to cellular membranes. Although AKT is a multidomain serine/threonine kinase composed of an N-terminal pleckstrin homology (PH) domain and a C-terminal kinase domain (KD), how these domains cooperate to regulate AKT activation on membranes remains...

Yuki Nakagaki, Toshiki Mori, Kenichi G. N. Suzuki et al. · Journal of the American Chem... · 0 citations