Author

Kenji Murakami

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Open access Sep 2026

Structural basis of a SWI/SNF-associated transcription pre-initiation complex.

The structural model suggests the coordinated actions of two DNA translocases, Snf2 of SWI/SNF and Ssl2 of TFIIH, for the initiation of transcription.

S. Nagai, Chun Yang, Dong-Hua Chen et al. · Cell · 1 citation

Open access Aug 2026

Clamp conformational flexibility and dynamics in archaeal and eukaryotic RNA polymerases revealed by cryo-EM

Cryo-electron microscopy is addressed using cryo-EM to examine archaeal RNAPs from Euryarchaeota and Crenarchaeota alongside yeast RNAP II and suggests that evolutionary tuning of clamp flexibility and dynamics contributes to distinct GTF-dependent promoter-loading mechanisms.

George Nkansah Rost Fordjour, L. Palao, Kenji Murakami et al. · Journal of Biological Chemis... · 0 citations