Kentaro Kuzuya

Autoimmune disease-associated pathobionts: mechanisms and therapeutic potential of phage-based approaches

The gut microbiota is a critical regulator of systemic immune homeostasis; accumulating evidence implicates specific commensal bacteria, termed “pathobionts,” in autoimmune disease pathogenesis. However, the definition of pathobionts remains context-dependent, as their effects are influenced by host genetics and host–m...