Morphological Basis of the Nephroprotective Effect of SGLT2 Inhibitors in Chronic Kidney Disease: A Systematic Review and Meta-Analysis
Background: Chronic kidney disease (CKD) is characterized by progressive loss of kidney function associated with intraglomerular hypertension, hyperfiltration, podocyte injury, tubular damage, and tubulointerstitial fibrosis. Sodium–glucose cotransporter 2 (SGLT2) inhibitors have demonstrated nephroprotective effects b...