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Kevin A. Seex

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Review Open access Sep 2026

The degenerating intervertebral disc leading to structural failure of the aging spine: from cellular pathways, risk factors, radiological diagnosis, to surgical management.

This perspective reviews the cellular pathways and risk factors contributing to disc degeneration specifically in an aging spine, as well as evolving surgical techniques and patient selection that may improve outcomes in patients that require structural intervention in their aging spine.

Victor Chen, Stone Sima, Owen Zhou et al. · 0 citations

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