Kevin M. De León González

Dynamin proline-rich domain isoform abundance, not identity, determines synaptic vesicle recycling efficiency in Drosophila

During neurotransmission, synaptic vesicle exocytosis adds membrane and proteins to the cell surface. To sustain further release, this material must be retrieved, via several distinct endocytic modes matched to the level of exocytosis. The GTPase dynamin plays a central role in endocytosis, but it has remained unclear...