Open access
Aug 2026
Balancing speed and separation: A high-throughput native mass spectrometry platform for screening complex bispecific antibody variants.
High-throughput liquid chromatography coupled to mass spectrometry (LC-MS) workflows are increasingly required to support the structural characterization of complex antibody formats such as multispecific (e.g. 2 + 1 and 1 + 1+1) and bispecific antibodies (bsAb) where misassembled product related variants pose significa...
Kyle Spitler, Kateryna Stepurska, Y. Liu et al.
· Talanta: The International J... · 0 citations