Abstract A103: Development of the cellular therapy barrier framework (CTBF): A computational transcriptomic approach to stratify pancreatic adenocarcinoma for precision cellular immunotherapy
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most treatment-resistant malignancies, with limited efficacy of cellular immunotherapy due to multiple interacting barriers within the tumor microenvironment. Existing molecular classifications describe tumor biology but do not comprehensively characteriz...