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Khulud Bukhari

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Open access Oct 2026

Integrated machine learning and structure-based discovery of noncovalent natural product inhibitors targeting SARS-CoV-2 papain-like protease

Papain-like protease is an essential severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enzyme involved in viral polyprotein processing and modulation of host innate immune responses, supporting its consideration as a viable target in antiviral research. Here, we present an integrated computational and expe...

Khulud Bukhari · 0 citations
Review Open access Aug 2026

Evaluating large language model performance in US FDA regulatory science

This study compares the performance of three LLMs in extracting, analyzing, and synthesizing regulatory and clinical information from FDA drug reviews, guidance for the industry, and drug labels as accessed through their standard user interfaces, using antibiotics approved for complicated urinary tract infections betwe...

Khulud Bukhari, R. Rodriguez-Monguio, B. Lopez-Bermudez et al. · 0 citations

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