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Author

Ki-Jun Yoon

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Open access Aug 2026

Aberrant excitatory neuronal ERBB4 promotes Alzheimer’s disease pathology

It is demonstrated that, during AD progression in mice, astrocytes and microglia increase phagocytic elimination of excitatory synapses while reducing elimination of inhibitory synapses, suggesting that neuroinflammation alone may be dispensable for early AD synapse loss.

Seyoung Lee, Eunseok Park, Ha-Eun Lee et al. · 2 citations · ⚡1
Open access Jul 2026

The m⁶A reader YTHDF2 regulates mRNA transport and axon outgrowth in developing neurons

It is found that the ablation of Mettl14 in postmitotic neurons leads to impaired axonal projection during corticogenesis, and the authors show that m6A RNA marks recruit YTHDF2-associated transport machinery that favors transport over degradation, localizing selected mRNAs to neurites to promote cortical axon projecti...

Bonsang Koo, Ajeet Kumar, H. Hwang et al. · 0 citations

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