Open access
Sep 2026
Rewiring Carbon Metabolism in Bacillus methanolicus via Heterologous Phosphoketolase Expression Enhances Biomass Yield From Methanol and Reduces CO2 Loss
The results show that PKT‐driven metabolic rewiring enhances substrate yields in B. methanolicus and provides a scalable strategy to improve methylotrophic bioprocesses and highlights carbon‐conserving pathway design as a key lever for advancing single carbon (C1) biomanufacturing.
Yael J. Toporek, J. Humphreys, Thomas J. Musselwhite et al.
· Microbial Biotechnology · 0 citations