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Author

Kimberly J. Hemmerling

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Open access Sep 2026

Reduced medial periventricular diffusion markers are associated with depressive symptoms and social deficits in ASD.

The glymphatic system is a candidate mechanism in autism spectrum disorder (ASD), linked to altered cerebrospinal fluid (CSF) dynamics, perivascular space (PVS) enlargement, and neuroinflammation, yet its relation to brain structure and clinical outcomes remains unexamined. We analyzed multimodal MRI (T2 FLAIR, T1, dif...

Faye McKenna, Kimberly J. Hemmerling, Sophie Molholm et al. · 0 citations
Open access Oct 2026

Multimodal MRI Clustering Reveals an Elevated Free-Water Biotype in Autism with Increased Social Symptoms

An ASD subgroup defined by extracellular fluid excess and altered white matter that is associated with greater social difficulties is identified, and this signature may help stratify individuals with ASD in mechanistic studies and clinical trials.

Faye McKenna, Kimberly J. Hemmerling, Shounak Nandi et al. · 0 citations

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