Tuberculosis (TB), caused by Mycobacterium tuberculosis, continues to be a major health issue worldwide. Granulomas are characteristic lesions of TB, functioning both as host defense structures and as sites where bacteria persist. To explore immune features associated with bacterial control versus disease progression,...
Malik Zohaib Ali, Taru S. Dutt, Johnathan Patterson et al.· Frontiers in Immunology· 0 citations
Abstract High-grade serous carcinoma (HGSC) of the ovary, fallopian tube, and peritoneum has an immunosuppressive tumor immune microenvironment (TIME), mediated in part by infiltrating innate immune cells such as macrophages, neutrophils, and myeloid-derived suppressor cells (MDSC). We hypothesize that manipulating the...
Railey G Mikeska, L. E. Feldman, Elizabeth R. Woodruff et al.· Cancer Research Communicatio...· 0 citations
Tumor innervation is established as a heterogeneous and clinically relevant feature of the NMIBC microenvironment, with neural abundance, phenotype, and spatial organization capturing distinct aspects of tumor behavior and clinical outcome.
Cailin S. Deiter, F. D. de Jong, M. Olislagers et al.· bioRxiv· 0 citations
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