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Kirsi Jahnukainen

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Case report Open access Sep 2026

Neurofibromatosis 1 (NF1) gene testing reveals rising variant allele fraction as an early warning sign of juvenile myelomonocytic leukemia.

Molecular analysis of the NF1 gene is part of the diagnostic criteria for neurofibromatosis type 1 (NF1) and is particularly useful in young children who do not yet exhibit sufficient clinical signs for diagnosis. Juvenile myelomonocytic leukemia (JMML) is a rare pediatric myelodysplastic/myeloproliferative neoplasm th...

S. Peltonen, Christian Johansson, Marika H. Grönroos et al. · 0 citations

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