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Kirstyn T. Carey

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Open access Sep 2026

Cell cycle dependent regulation of mRNA export in response to replication stress

Nuclear export of mRNA is extensively coupled to transcription and processing of mRNA. How mRNA export is mechanistically regulated remains poorly understood. Here, we uncover a physical checkpoint at nuclear speckles that regulates mRNA export during DNA replication in S-phase of the cell cycle. Unbiased screening app...

Tobias D. Williams, Kirstyn T. Carey, W. Hamilton et al. · 0 citations

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