Review
Open access
Oct 2026
From danger to resolution: targeting purinergic signaling in CNS diseases
The central nervous system (CNS) is a dynamic immunological environment, where specialized interfaces, immune reservoirs, and metabolic clearance pathways, such as the glymphatic system, orchestrate immune surveillance and homeostasis. Within this intricate network, purinergic signaling, mediated by nucleotides like AT...
Camille Degryse, Kirti Gupta, Luc Buée et al.
· Medicinal Chemistry Research · 0 citations