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Kiya C. Jackson

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Open access Sep 2026

Precocious maturation and Purkinje cell dysfunction in the mouse Chd8 haploinsufficient cerebellum

The cerebellum plays an emerging, but understudied, role in neurodevelopmental disorders (NDDs). Mutations in CHD8 cause a monogenic NDD (CHD8-NDD) characterized by autism and other manifestations, and prior work in Chd8 mutant mice reported cerebellar abnormalities, raising the possibility of cerebellar contribution t...

Nicolas Seban, Esteban Merino, Alexa D'Ambra et al. · 0 citations

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