Author

Klaudia Dynarowicz

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Review Open access Oct 2026

Porphyrin-Based Compounds in Medicine: From Photodynamic Therapy to Theranostics

Porphyrins and their derivatives represent one of the most adaptable classes of compounds in contemporary biomedical research, bridging the crucial gap between diagnostic imaging and therapeutic intervention. This comprehensive review examines the evolution of porphyrin-based compounds and their therapeutic application...

Urszula Rodzoń-Wańczura, D. Aebisher, Tamil Selvan Ramesh et al. · Molecules · 0 citations

#graph neural networks Review Open access Oct 2026

Artificial Intelligence in Photodynamic Therapy: From Molecular Design of Photosensitizers to Intelligent Delivery, Adaptive Dosimetry, and Personalized Prognostication of Results

Photodynamic therapy (PDT) is a minimally invasive therapeutic approach based on the light-induced activation of a photosensitizer in the presence of molecular oxygen, resulting in the generation of reactive oxygen species, including singlet oxygen. Despite local selectivity and low systemic toxicity, reproducibility o...

R. Marunych, D. Bartusik-Aebisher, Klaudia Dynarowicz et al. · International Journal of Mol... · 0 citations

Review Open access Aug 2026

Photodynamic Therapy in Cancer: Mechanisms, Photosensitizer Technology, Vitamin Modulation, and Rational Combination Design

Overall, PDT combination design should be guided by whether adjunctive agents support or undermine photosensitizer accumulation, oxygen availability, ROS-mediated cytotoxicity, and immune activation, when selected according to mechanistic compatibility.

Ilaf Naser, D. Bartusik-Aebisher, Barbara Smolak et al. · Biomedicines · 1 citation