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Open access Aug 2026

Immunological risk identified by single-cell multi-omics and cardiovascular outcomes.

BACKGROUND AND AIMS While inflammation and (auto-)immunity are modifiers of atherosclerosis, immunological determinants of cardiovascular risk beyond the established inflammatory markers, high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6) remain incompletely defined in humans. This exploratory proof-o...

H. Horstmann, Nathaly Anto Michel, C. Losert et al. · 0 citations
Jul 2026

Single-Cell Multi-Omics Reveals T Cell Dysregulation in Sarcoidosis 2310194

Sarcoidosis is a systemic inflammatory disease characterized by granulomatous inflammation that affects multiple organs. Prior studies suggest that infection may trigger an antigen-mediated T cell response. However, the underlying immunological mechanisms remain largely unclear. Understanding these mechanisms is...

Nandeeni Suryawanshi, Neal L. Weintraub, Catherine C. Hedrick et al. · 0 citations

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