Author

Koji Nobe

2 papers indexed here

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Open access Aug 2026

Multifaceted renoprotection by SMTP-44D in diabetic nephropathy: Targeting inflammation, oxidative stress, and insulin resistance.

Diabetic nephropathy (DN) is a major complication of diabetes and a leading cause of dialysis initiation. However, treatment options for DN are currently limited, highlighting the urgent need for novel therapies. The pathogenesis of DN involves persistent chronic hyperglycemia and advanced glycation end products, leadi...

Taiki Awane, K. Shibata, Daisuke Saigusa et al. · Experimental and molecular p... · 0 citations

Open access Sep 2026

SMTP-44D Attenuates Renal Inflammatory/Oxidative Dysfunction in a Mouse Model of Ischemia–Reperfusion-Induced Acute Kidney Injury

Functional and molecular findings suggest that SMTP-44D provides anti-inflammatory and antioxidant renoprotection, while evidence supporting structural protection is lacking in the pre-ischemic administration protocol.

K. Shibata, Keiji Hasumi, Koji Nobe · International Journal of Mol... · 0 citations