Open access
Aug 2026
Exploration of non-hydroxamate based quinoline analogues as HDAC8 inhibitors
Novel non-hydroxamate-based quinoline analogues were designed and explored as HDAC8-selective inhibitors that exhibit nanomolar HDAC8 enzymatic inhibition and establish these compounds as promising HDAC8 modulators with potential for therapeutic development in neuroblastoma.
N. V. M. Rao Bandaru, Vandana Joshi, M. Schweipert et al.
· RSC Advances · 0 citations