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Kong-Cai Zhu

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Open access Aug 2026

Metabolomics and Machine Learning Uncover 5′-Methylthioadenosine as a Metabolic Indicator of Mixed-Pattern Drug-Induced Liver Injury

MTA emerges as an exploratory biomarker that uncovers the distinct metabolic trajectories hidden within mixed-pattern DILI, and these findings highlight the MTA-methylthioadenosine phosphorylase phosphorylase (MTAP) axis as a potential mechanistic driver of cholestatic injury.

Jing-Hui Zhang, Hong-Chuan Liu, Qi Qiu et al. · 0 citations

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