Radiation dosimetry for the reactive astrogliosis positron emission tomography tracer [¹⁸F]SMBT-1 in healthy human
[¹⁸F]SMBT-1 is a prominent positron emission tomography (PET) tracer developed as a selective and reversible imaging probe for monoamine oxidase B (MAO-B). MAO-B is overexpressed in reactive astrocytes and serves as a surrogate biomarker for astrogliosis, a component of neuroinflammation. However, internal radiat...