Protein Phosphatase 2A Modulates AKT-Mediated Macrophage Polarization in Adipocyte-Induced Inflammation.
Obesity and type 2 diabetes mellitus (T2DM) are associated with chronic low-grade inflammation that sustains insulin resistance and metabolic dysfunction. Adipose tissue, through the secretion of adipokines and cytokines, plays a central role in shaping macrophage polarization and maintenance of an inflammatory microen...