Emerging Roles of TMEM97/Sigma-2 Receptor in Breast Cancer Endocrine Resistance: Links to mTOR Signaling and Cholesterol Metabolism
Breast cancer remains one of the most common cancers in women, in which the majority of cases exhibit a hormone receptor-positive subtype. Although several treatment options are available for patients with this subtype, first-line therapies mainly rely on the patient’s sensitivity to endocrine therapy. Therapy resistan...