Open access
Jul 2026
Long-read, whole-genome sequencing and chemotherapy response of two patient-derived organoids from a TP53- and KRAS-mutant ovarian carcinoma
Two PDOs with differential responses to carboplatin derived from sequential ascites fluid collections from a patient with high-grade müllerian carcinoma are described and the ability of long-read sequencing to add detail into the genomics and epigenetics of ovarian cancer is demonstrated.
J. Wendt, Kristin M. Adams, Ryan Moreno et al.
· bioRxiv · 0 citations