Kulddep Kumar Roy

Abstract B136: In Silico Screening and Biological Evaluation of Traditional Chinese Medicines library against Switch-II Pocket of KRASG12D in pancreatic Cancer

KRASG12D is a common cancer-driving mutation that fuels aggressive cancers, most notably in pancreatic, colorectal, and lung cancers. Although its role in disease progression is well established, treatment options that directly target KRASG12D are still limited. In this study, we employed a structure-based virtual sc...