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Open access Oct 2026

Recurrent gene conversions and subcluster-specific variants are associated with Mycobacterium tuberculosis adaptation to intensive host pressure: a comparative genomic study

Long-read sequencing has revealed complex variations, such as gene conversions in immunologically critical PE/PPE gene families, yet their role in Mycobacterium tuberculosis host adaptation remains unclear. We performed a comparative genomic analysis across a gradient of host-imposed selective pressure...

Tian-Yu Lin, Kun Chen, Zhen-Chun Chen et al. · 0 citations

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