Open access
Sep 2026
Nickel‐Catalyzed Negishi Coupling for Modular and Diverse Synthesis of Sulfonyl Fluorides and Sulfonamides †
Sulfonyl groups represent one of the most encountered structural motifs in medicinal chemistry. They serve as stable linkers that connect pharmacophoric elements within a molecule and as modulators of physicochemical properties, including lipophilicity, conformational flexibility, and metabolic susceptibility. This v...
Chen-Hui Jiang, Yi-Gang Yang, Zhi-Kun Zhang et al.
· Chinese journal of chemistry · 0 citations