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Author

Kwok-Wai Lo

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Aug 2026

Epstein-Barr Virus-Mediated Tumorigenesis in Nasopharyngeal Carcinoma.

Effective screening program of risk individuals in endemic populations will allow detection of early-stage NPC that is more amenable to cure utilizing treatment regimen with reduced toxicity while targeting EBV's pathogenic mechanism in NPC will enable the development of novel therapeutic strategy against metastatic an...

A. K. Chiang, Kwok-Wai Lo, Mu-Sheng Zeng · 0 citations
Open access Jul 2026

Long-read sequencing reveals widespread novel splicing and neojunction-derived neoantigens in nasopharyngeal carcinoma

Long-read sequencing is employed to generate a high-resolution, isoform-level transcriptomic atlas from a cohort of 14 NPC tumor samples and four immortalized nasopharyngeal epithelial cell lines, and a new class of noncanonical neoantigens with significant potential for developing personalized cancer vaccines for NPC...

Yi Shuai, Hualiang Yao, Bo Wang et al. · 0 citations
Review Open access Aug 2026

The roles of chromatin remodeling and 3D genome organization in cancers: from mechanistic insights to emerging treatment options

A comprehensive synthesis of the mechanisms and functional roles of classical chromatin remodelers within both physiological and neoplastic contexts is provided and a hierarchical framework that distinguishes between 'first-level' and 'higher-order' chromatin remodeling is proposed.

Chu-Qiao Luo, Ning-Lin Xia, Shin-Yee Hui et al. · 0 citations

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