Author

Kyle R. Whitson

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Open access Oct 2026

Pharmacokinetics and safety of dolutegravir in term neonates exposed to HIV-1 (IMPAACT 2023): a phase 1, open-label, multicentre study.

BACKGROUND Safe and effective antiretroviral options are needed for neonates exposed to HIV-1, but data supporting dolutegravir use from birth are scarce. The aim of this study was to evaluate dolutegravir pharmacokinetics, safety, and tolerability in term neonates, and to identify an appropriate dosing regimen. METH...

J. Momper, Jia-Jia Wang, Sarah Bradford et al. · The Lancet HIV · 0 citations

Oct 2026

Safety, antiviral activity, and pharmacokinetics of long-acting cabotegravir plus long-acting rilpivirine in virologically suppressed adolescents living with HIV-1 (IMPAACT 2017/MOCHA): week 96 and end-of-study results from a multinational, phase 1/2, single-arm trial.

BACKGROUND Week 24 and week 48 study data from the International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT 2017)/More Options for Children and Adolescents (MOCHA) trial supported the use of long-acting cabotegravir plus long-acting rilpivirine, given every 4 weeks or 8 weeks, per the adult dos...

Carolyn Bolton Moore, K. Baltrusaitis, E. Capparelli et al. · The Lancet Child & Adolescen... · 0 citations