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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Kyung-Hoon Kim

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Review Open access Oct 2026

Opiranserin (VVZ-149): what’s new in analgesics

Opiranserin (VVZ-149) is a novel non-opioid, non-steroidal intravenous analgesic with triple antagonistic activity at glycine transporter 2 (GlyT2), purine 2 receptor 3 (P2X3), and serotonin receptor (5-HT2A). Its half-maximal inhibitory concentrations are 0.86, 0.87, and 1.3 μM for GlyT2, P2X3, and 5-HT2A, in the orde...

Kyung-Hoon Kim · 0 citations

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