Open access
Aug 2026
Distinct metabolic phenotypes in adolescents with obesity identified by unsupervised learning: associations with insulin resistance and resting energy expenditure
Background Pediatric obesity is characterized by substantial metabolic heterogeneity, including adiposity, insulin resistance, inflammation, and energy metabolism. Traditional categorical classifications may inadequately capture this complexity. Objective: To identify clinically meaningful metabolic phenotypes using un...
A. Sonza, S. Tamini, A. Bondesan et al.
· Frontiers in Endocrinology · 0 citations