HPV16 transcriptional patterns in oropharyngeal squamous cell carcinoma with different clinical outcomes
Human papillomavirus (HPV) 16 is the leading cause of oropharyngeal squamous cell carcinoma (OPSCC) in many Western countries. Although patients with HPV16-positive OPSCC generally have better outcomes than those with HPV-negative disease, significant heterogeneity exists, and a subset of these patients still experienc...