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Author

L. Barba

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Open access Oct 2026

Tau isoform mapping across tissues and biofluids reveals a signature distinguishing Alzheimer’s disease from amyotrophic lateral sclerosis

Blood phosphorylated tau 217 (p-tau217) accurately detects Alzheimer’s disease (AD) pathology but is also elevated in amyotrophic lateral sclerosis (ALS), likely reflecting peripheral (big) tau released from muscle. Assays selectively measuring brain-derived (BD-) tau and BD-p-tau217 are therefore needed. We analysed s...

S. Abu-Rumeileh, H. Großkopf, Arthur Guthknecht et al. · 0 citations
Sep 2026

Whole-body quantitative muscle MRI in myotonic dystrophy type 2: a sensitive tool for pattern recognition, disease stratification and objective assessment of clinical severity

Background Myotonic dystrophy type 2 (DM2) is a frequent yet underdiagnosed muscle disorder. Although muscle MRI is increasingly used in neuromuscular disorders, there is an overt lack of evidence regarding its role in DM2. This study aimed to characterise whole-body muscle involvement using semiquantitative and quanti...

Alexander Mensch, M. Heuschen, L. Barba et al. · 0 citations
Open access Sep 2026

Role of Thrombectomy Technique in Alteplase Bridging Intravenous Thrombolysis for Basilar Artery Occlusion.

BACKGROUND Endovascular treatment (EVT) is the standard of care for acute basilar artery occlusion (BAO) although the role of bridging intravenous thrombolysis (IVT) with alteplase prior to EVT remains debated. Whether the effect of bridging IVT differs across EVT techniques has not been systematically assessed. METH...

Muhammad Jaffar, K. Ahmed, S. Abu-Rumeileh et al. · 0 citations
Open access Aug 2026

Decoding the causes of ischemic stroke despite ongoing oral anticoagulation and their clinical impact: the ASPERA-R study

Potential causes of breakthrough ischemic stroke are identifiable in about half of breakthrough strokes and are associated with higher risk of recurrence compared with those without, warranting individualized approaches.

Federico De Santis, Matteo Foschi, Francesca Gabriele et al. · 0 citations

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