Clinical, Laboratory, and Molecular Markers of Type 3 von Willebrand Disease
Type 3 von Willebrand disease (VWD3) is due to a virtually complete deficiency of von Willebrand factor (VWF), and it is inherited as an autosomal recessive trait: heterozygous relatives have mild or no bleeding symptoms. The prevalence of VWD3 is very low, ranging from 0.1 to 5.3 per million population. VWD3 patients...