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Author

L. Buccini

2 papers indexed here

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Open access Sep 2026

Rational design of microfluidic liposome formulations: Integrating flow control with multi-analytical characterization.

Liposomes are vesicular structures consisting of one or more lipid bilayers that enclose an aqueous inner core, allowing the encapsulation of both hydrophilic compounds in the inner compartment and lipophilic and amphiphilic molecules within the lipid bilayer. In recent years, microfluidic-based manufacturing technique...

E. D'Intino, F. R. Stacchini, L. Buccini et al. · 0 citations
Open access Aug 2026

Plasma Gelation as an Overlooked Determinant of Transfection Efficiency in Protein Corona‐Coated Lipid Nanoparticles: Implications for In Vitro–In Vivo Translation

A combination of complementary approaches, including dynamic light scattering, fluorescence‐activated cell sorting, confocal fluorescence microscopy, raster image correlation spectroscopy, and functional assays evaluating TE and cell viability, demonstrates that this gel‐like matrix restricts LNP diffusion in the extra...

Serena Renzi, L. Digiacomo, Francesca Giulimondi et al. · 1 citation

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