Author

L. Chouliaras

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Open access Sep 2026

Interrogating DNA methylation associated with Lewy body pathology in a cross brain-region and multi-cohort study

Here, we conduct a large meta-analysis of DNA methylation across multiple cortical brain regions, in relation to increasing burden of Lewy body pathology. Utilizing a dataset of 1205 samples (832 unique donors), we identify 24 false discovery rate significant differentially methylated loci associated with Lewy body...

Joshua Harvey, J. Imm, Morteza Kouhsar et al. · Nature Communications · 0 citations

Open access Jul 2026

Metabolism Pathway Blood Proteomic Differences in Lewy Body Dementia Compared to Alzheimer’s Disease

Dementia with Lewy Bodies (DLB) is the most common neurodegenerative dementia after Alzheimer’s disease (AD), but it remains challenging to diagnose due to overlapping symptoms and mixed pathologies. This pilot study tested whether DLB has different metabolic blood proteomic profiles compared to AD and controls. Serum...

Ariana Pritha, L. Chouliaras, P. Swann et al. · International Journal of Mol... · 0 citations

Open access Jul 2026

Blood-based immunophenotyping of T cell profiles in patients with neurodegenerative disorders.

Examination of blood-based T-cell profiles across a range of neurodegenerative dementias provides evidence that T-cell dysregulation is not unified in patients with neurodegenerative diseases and observes different involvement across different dementia types establishing adaptive immunity as a key contributor to diseas...

Frederika Malichova, P. Swann, S. Kigar et al. · Alzheimer's Research & Thera... · 0 citations