Author

L. Cornelis

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Open access Oct 2026

Large-scale cerebrospinal fluid proteomics identifies diagnostic biomarker candidates across the clinico-pathological continuum of frontotemporal lobar degeneration

Frontotemporal lobar degeneration (FTLD), predominantly comprised of tau and TDP-43 proteinopathies, is a common cause of early-onset dementia. Biomarkers that reliably classify FTLD subtypes are limited, thereby hindering in-vivo diagnosis and clinical trial stratification. We conducted large-scale, multi-platform cer...

R. Saloner, L. Cornelis, Joshua Downer et al. · bioRxiv · 0 citations

Open access Sep 2026

Blood proteomics of menopause map to brain aging and dementia risk.

It is shown that spontaneous menopause is characterized by dysregulation in inflammatory, synaptic, metabolic and Alzheimer's disease biologic processes, which tracked more strongly with hormones than with age.

Madeline Wood Alexander, Jennifer S. Rabin, Michelle R. Caunca et al. · Nature Medicine · 1 citation