Author

L. D. Williams

2 papers indexed here

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Open access Sep 2026

Preferential engagement of the anti-inflammatory ATP/adenosine axis by HIV vaccine candidate with V1-deleted envelope in male rhesus macaques

Summary We evaluate the efficacy and immunogenicity of HIV clade A/E A244 envelope (Env) immunogens with the 23 amino acids of variable region 1 deleted (ΔV1) or retained (wild-type [WT]) in macaques. Only the ΔV1 regimen significantly reduces the risk of mucosal acquisition of clade C simian/human immunodeficiency vir...

Isabela Silva de Castro, Mohammad Arif Rahman, Massimiliano Bissa et al. · Cell Reports Medicine · 0 citations

Open access Jul 2026

Rapid and robust immune response boosting with potent, next-generation adjuvant in viral vector-primed primates

ABSTRACT To identify strategies for augmenting vaccine immunogenicity, we compared a pox-protein prime-boost regimen comprising recombinant modified vaccinia virus Ankara and multimeric HIV-1 Env gp145, adjuvanted with Army Liposomal Formulation (ALF) either adsorbed to aluminum salt (ALFA) or formulated with the QS-21...

Hannah A. D. King, C. Subra, Emily Tourtellott et al. · Journal of Virology · 0 citations